Fig. 4From: Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stressHousing temperature alters bulk histone acetylation, but not methylation, in BAT and has no effect on bulk histone acetylation or methylation in liver. Percent (A) acetylated (1 + acetylation) and (B) methylated (1 + methylation) histones H3.2 and H4 isolated from liver and BAT. Number of (C) acetyl groups and (D) methyl groups (K4me2 = 2 methyl groups) per histones H3.2 and H4 isolated from liver and BAT. n = 3–5 per group. One-way ANOVA testing was conducted for all histone data from each tissue comparing TN, RT, and SC housing conditions, and p-values are indicated in each plot. TN: thermoneutral. RT: room temperature. SC: severe coldBack to article page