Fig. 5From: De novo methylation of histone H3K23 by the methyltransferases EHMT1/GLP and EHMT2/G9aGenetic ablation of GLP, G9a, or both, decreases H3K9 and H3K23 methylation in vivo. Mouse embryonic stem cells were knocked out for GLP, G9a, or both genes, and whole cell extracts were subjected to western blotting with the indicated antibodies to evaluate changes to levels of H3K9 and H3K23 methylation states in vivoBack to article page