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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: The cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elements

Fig. 2

Distribution of repeat sequences and the co-binding consensus for BORIS and CTCFsites. a The chart showing the breakdown of repeat types among the features that are strongly bound (×4 enrichment or more) by both BORIS and CTCF, based on 171 ChIP-seq-validated repeats in Additional file 1: Table S2. b The co-binding DNA consensus derived from 171 co-bound repeats. c The whole-genome consensus for CTCF binding based on ChIP-seq data with the same parameters as in b. d The larger duplicate/staggered consensus for 171 repeats, when a 40-nucleotide window was interrogated. CTS’ denotes a short consensus for CTCF binding. e A model explaining the “staggered” emergence of cluster CTSs from tandem TRs containing CTS’

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Epigenetics & Chromatin

ISSN: 1756-8935