Fig. 3
From: The histone chaperone DAXX maintains the structural organization of heterochromatin domains
Aberrant spatial relationships between H3K9me3 and major satellite DNA. FISH of major satellite DNA (red) and immunofluorescence (IF) microscopy of H3K9me3 (green) of wild type (a) and DAXX null (b) fibroblasts. Magnified chromocentres are marked by white boxes in the merged images. Two independent line scan intensity plots are shown for each enlarged chromocentre. Dashed solid arrows indicate the line scan plot and direction of the first (left) and second (right) histograms, respectively. Scale bar 5 µm. c Quantification of the percentage of typical versus atypical H3K9me3-enriched chromatin domains from each cell line. Error bars SEM