Figure 5

CycG misregulation alters homeotic transformations of a Pc mutant. (A) Penetrance of L2 and L3 ectopic sex combs in Pc ³/+, Pc ³/+;da > CycG RNAi and Pc ³/da > CycG ^ΔP males. Fisher’s exact test, **P < 0.0001 (n ≥ 58). (B) Penetrance of wing to haltere transformations in Pc ³/+, Pc ³/+;da > CycG RNAi and Pc ³/da > CycG ^ΔP females and males. Fisher’s exact test, **P < 0.0001 (n ≥ 31). (C) Representative Pc ³/+ adult female wing with posterior deformation corresponding to a partial transformation into haltere tissue (arrowhead). Representative Pc ³/da > CycG ^ΔP female wing with suppressed haltere to wing transformation. (D) Penetrance of A4 to A5 abdominal segment transformations in Pc ³/+, Pc ³/+;da > CycG RNAi and Pc ³/da > CycG ^ΔP males. Fisher’s exact test, *P < 0.05, **P < 0.0001 (n ≥ 29). (E) Abdomens of Pc ³ and Pc ³/+;da > CycG RNAi males with representative A4 to A5 transformations (arrowheads). A4, A5, A6: abdominal segments 4, 5, and 6.