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Figure 8 | Epigenetics & Chromatin

Figure 8

From: DNA demethylation by 5-aza-2′-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences

Figure 8

No effect on primary transcript levels was found with 5-aza-CdR exposure. The Intronic Retention Score (IRS) was calculated for each condition, with the loci changing 2× the standard deviation depicted by green (increased) or red (decreased) as a response to the drug exposure. No systematic shift to increased IRS with drug exposure was found, a finding that makes it unlikely that the primary RNA transcript is influenced by gene body demethylation by 5-aza-CdR. 5-aza-CdR, 5-aza-2′-deoxycytidine.

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Epigenetics & Chromatin

ISSN: 1756-8935