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Figure 1 | Epigenetics & Chromatin

Figure 1

From: Nucleosomes are enriched at the boundaries of hypomethylated regions (HMRs) in mouse dermal fibroblasts and keratinocytes

Figure 1

Patterns of nucleosome occupancy at hypomethylated regions (HMRs) of mouse fibroblasts and keratinocytes. (a-c) Heatmap of nucleosome densities at HMRs sorted by length in fibroblasts (Fb.) for (a) all HMRs, (b) HMRs overlapping with CGIs and (c) HMRs not overlapping with CGIs. (d-f) Average nucleosome occupancy measured in fibroblasts (blue) and keratinocytes (red) and intrinsic nucleosome occupancy scores (INOS, black) for (d) all fibroblast HMRs, (e) fibroblast HMRs overlapping CGIs (+CGIs), and (f) non-CGI containing fibroblast HMRs (-CGIs). HMRs are aligned by the first (5′) unmethylated CG dinucleotides. (g-i) same as in (a-c) but for mouse keratinocytes (Ker).

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Epigenetics & Chromatin

ISSN: 1756-8935