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Table 3 Telomere lengths in members of the ring 17 family and in normal age-matched individuals

From: Telomere shortening and telomere position effect in mild ring 17 syndrome

 

Age (years)

Cell scored

Mean cellular telomere length

Normal metaphases

Ring metaphases

    

17p arm +17q arm

17p arm +17q arm (homolog of ring chromosome)

17p arm +17q arm (ring chromosome)

III-1

10

51*

53.0 ± 4.6

103.7 ± 9.2

94.5 ± 6.3

48.1 ± 5.6

cntr1

10

20

75.1 ± 6.5

108.9 ± 8.9

  

cntr2

11

20

91.4 ± 7.4

153.9 ± 11.8

  

cntr3

12

20

117.8 ± 11.3

193.3 ± 16.5

  

cntr4

12

20

95.5 ± 8.4

163.7 ± 14.1

  

II-1

30

19

49.9 ± 5.6

71.9 ± 7.7

  

II-2

34

68**

54.0 ± 4.8

77.0 ± 4.2

66.8 ± 4.6

75.9 ± 5.6

cntr5

33

20

50.5 ± 3.6

68.7 ± 6.0

  

cntr6

33

20

63.8 ± 6.0

62.7 ± 6.1

  

cntr7

33

20

49.1 ± 4.3

60.7 ± 3.6

  

cntr8

37

20

45.7 ± 3.6

76.0 ± 4.2

  

cntr9

37

20

80.9 ± 7.7

132.7 ± 14.9

  
  1. Data are shown for all the individuals analyzed. *18 normal metaphases and 33 carrying the ring 17 chromosome. **46 normal metaphases and 22 carrying the ring 17 chromosome.