Figure 7From: Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progressionSMARCA5 associates with candidate replication origins during S-phase. Serum-starved (SS, 0 h) NIH3T3 cells were released into S-phase in the presence of DMSO or 3 μM 898. SMARCA5 occupancy at α-globin (early replicating origin), pancreatic amylase (mid-late replicating) and β-globin (late replicating) in synchronous NIH3T3 cells were determined using chromatin immunoprecipitation (ChIP) assays. Average fold enrichment for SMARCA5 relative to input from two independent experiments is shown.Back to article page