Figure 1From: Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotesDNA and histone H3 methylation in mouse, bovine and rabbit zygotes at advanced pronuclear stages. Representative images (>20 zygotes for each case) of indirect fluorescent immunostaining using specific antibodies against: (A) methylated cytosine residues (5meC); (B) H3K9me2 and (C) H3K4me3. The asymmetry in 5meC and H3K9me2 signal intensities between paternal and maternal pronuclei of mouse, bovine and rabbit zygotes are clearly visible in lanes A and B respectively. H3K4me3-specific signal (lane C) is present in both pronuclei. Scale bar 20 μm.Back to article page