Fig. 8

H3K9me3 domain positions relative to genes and transcriptional activity. A Coverage of genome functional regions by H3K9me3 domains. B Number of genes overlapped at least partially by H3K9me3 domains. C Expression levels of genes according to their coverage extent by H3K9me3 domains. For each coverage range class, the expression level (TPM) distribution of the corresponding genes is plotted above. TPM distributions of PGCs and ESCs are highly significantly different for all classes excepted the 50% to 75% class (p < 0.001 based on the Wilcoxon–Mann–Whitney test)