Fig. 2From: Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stressAlternative splice variants and reduced representation bisulfite sequencing (RRBS) data reveal changes in brown adipose tissue associated with housing temperature. (A) A comparison of SC vs TN housing RNA-Seq data reveals differential expression of alternate splice variants in BAT. Integrated RNA-Seq and RRBS data for (B) SC vs TN housed mice. (C) SC vs RT housed mice; and (D) RT vs TN housed mice. n = 4 per group for RNA-Seq and RRBS datasets. RRBS data shown are for percent methylation difference >|5|, padj < 0.05. DEG: differentially expressed genes. DMP: differentially methylated promoters. DMG: differentially methylated genes. TN: thermoneutral. RT: room temperature. SC: severe coldBack to article page