Figure 5
From: Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae
Histone modifiers are required for silencing but not nucleosome positioning at telomeres. (A) Frequency of fluoroorotic acid (FOA) resistance in isogenic Δbre1::KanMX, Δdot1::KanMX, Δset1::KanMX, Δsas2::KanMX, and Δbdf1::KanMX strains containing the URA3-yEGFP marker adjacent to the core X element at the indicated telomere. The mean and standard deviation of FOA resistance is given for each strain. (B) The subtelomeric chromatin structure of the XIL telomere was analysed in the Δbre1::KanMX, Δdot1::KanMX, and Δbdf1::KanMX strains, by MNase digestion and indirect end labelling, as for Figure 1B.